Note that after Isaac wins the fight, he should aim (in third person) at the enemy and fire.
Spam the action button to get outta Dodge. There are a few quick time events (QTEs) to deal with before you get into earnest killing. It seems the game will fully heal Isaac just as the final battle begins, saving you the medkits for later use. Under no circumstances should you try to heal. Stasis is optional for the final boss if you fire quickly enough.
If you need to, reload your weapons and wait for the stasis meter to recharge fully. The regenerator chases you up to the walkway to the Marker. Break the fuse and head through the left of the two doors (the right is a balcony, and may delay your progress, allowing the regenerator to catch up). If you are playing Hard Core and haven't used up all three of your saves, you might consider using it. There is one last save station right before the battle. Locate the lift to the upper level of the stage - at that point, all the enemies except the regenerator will leave Isaac alone. Just don't stay too long, as the regenerator slowly plods to come at you. Note that the interiors are not a good defence againts Slashers and the other enemies, but it does provide cover from Pukers on the walkway. Since you only need the Plasma Cutter's ammo (30 to 40 would be handy for the final battle, depending on your DMG nodes - IGN prefers maximum for DMG), use the other ammo (line Gun or Contact Beam) for fighting off the horde. If you want to simplify logistics, just take the two or three weapons you need instead of all four.Įnemies appear once you exit the doors to the Marker's base. Remember the regenerating necromorph will continue to chase Isaac all the way up to the final walkway to the boss. Stasis shots with the Contact Beam are handy when surrounded, and the medkits are for muscling through the battle. The weapons you (preferably) need will be a mix of mass-kill/quick-reaction and single-target/rapid-fire weapons.Įssentially, the Plasma Cutter is for the boss (empty the clip in the last boss) while the Contact Beam (or Line Gun) is for stopping (stasis) or killing the hordes of enemies in the final stage. The final save/store/workbench combination before the final stage.
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